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Board of Regents download images at HathiTrust Journal of browser. For commercial re-use, please contact journals. Abstract As a cofactor in numerous enzymatic reactions, magnesium fulfils various intracellular physiological functions. Thus, imbalance in magnesium status—primarily hypomagnesaemia as it is seen more often than hypermagnesaemia—might result in unwanted neuromuscular, cardiac or nervous disorders.
Measuring total serum magnesium is a feasible and affordable way to monitor changes in magnesium status, although it does not necessarily reflect total body magnesium content.
The following review focuses on the natural occurrence of magnesium and its physiological function. The absorption and excretion of magnesium as well as hypo- and hypermagnesaemia will be addressed. Keywords: magnesium, physicochemical properties, physiological function, regulation, hypomagnesaemia, hypermagnesaemia Introduction Magnesium is the eighth most common element in the crust of the Earth [ 1 , 2 ] and is mainly tied up within mineral deposits, for example as magnesite magnesium carbonate [MgCO3] and dolomite.
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